MICROSPHERES A MAGICAL NOVEL DRUG DELIVERY SYSTEM: A REVIEW
*Preeti Agrawal1, Sarlesh Rajput1, Ashish pathak1, Nikhil Shrivastava2, Satyendra Singh Baghel2, Rajendra singh Baghel2
1Department of Pharmaceutics, ShriRam College of Pharmacy, Morena, M.P., India
2Department of Pharmacology, ShriRam College of Pharmacy, Morena, M.P., India
ABSTRACT
Drug delivery systems (DDS) that can precisely control the release
rates or target drugs to a specific body site have had an enormous
impact on the health care system. So the concept of targeted drug
delivery is designed for attempting to concentrate the drug in the
tissues of interest while reducing the relative concentration of the
medication in the remaining tissues. As a result, drug is localized on
the targeted site. Hence, surrounding tissues are not affected by the
drug. So, carrier technology offers an intelligent approach for drug
delivery by coupling the drug to a carrier particle such as
microspheres, nanoparticles, liposomes, etc which modulates the
release and absorption characteristics of the drug. Among these drug
delivery system we are selecting microspheres of various types which
will be controlled release and which can be made specific site targeted
by giving some specific characteristic to it like mucoadhesion character or by inserting any
magnetic or radioactive material as a result of which it will show site specific action. So this
article emphasis on different types of microspheres as a controlled and targeted drug delivery
system.
Keywords: Microsphere, target site, Specificity, controlled release.
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