Abstract

AN OVERVIEW OF: VESICULAR DRUG DELIVERY SYSTEM

*Mohammad Zishan, Poonam Kushwaha, Kuldeep Singh, Mohammad Amir, Vaseem A Ansari, Anup Kumar Sirbaiya and Satya Prakash Singh

ABSTRACT

The objective of the study is to evaluate the potential of novel vesicular drug delivery systems for drug targeting. Novel vesicular drug delivery systems aim to deliver the drug at a rate directed by need of body during the period of treatment and channel the active entity to the site of action. The conventional drugs have short residence time at the site of application and poor bioavailability which leads to incomplete elimination of organisms causing reoccurrence and tolerance. Recently, vesicular mode of delivery of drugs has gained attraction because of its improved therapeutic efficacy and stability. Vesicles are bilayered structures formed by hydration of lipid molecules and can be used for incorporating both hydrophilic and lipophilic drugs. This paper focus on various vesicular systems such as liposomes, niosomes, ethosomes, transferosomes.

Keywords: Vesicular system, Types of vesicular drug delivery system, Limitation.