Abstract

DESIGN, DEVELOPMENT AND EVALUATION METHODS FOR PREPRATION OF TRANSDERMAL PATCHES

Ragini Verma*, Prof. Dr. S.K. Prajapati, Prashant Kumar Singh and Pankaj Kumar Singh

ABSTRACT

In recent years, a variety of pharmaceutical research has been conducted to develop new dosage forms. Among the dosage forms developed to facilitate simplicity of medication, Transdermal drug delivery system is one of the most widely employed for commercial products. As our society is becoming increasingly aged, the development of Transdermal patchs have been formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water. Such formulations provide an opportunity for product line extension in the many elderly persons will have difficulties in taking oral dosage forms (viz., solutions, suspensions, tablets, and capsules). To improve characters of transdermal drug delivery system (TDDS) was emerged, which will improve the therapeutic efficacy and safety of drugs by specific sites within the body, thereby reducing both the size and number of doses. This review article describes all information related to TDDS such as advantage, active ingredients, factors affecting TDDS, markets products, mechanism of acton, types, method of prepration and methods of evaluations.

Keywords: Transdermal Drug Delivery System (TDDS), Partition coefficient, Reservoir, etc.