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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

DEVELOPMENT & VALIDATION OF A UV VISIBLE SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF LOVASTATIN IN BULK AND PHARMACEUTICAL DOSAGE FORM.

Narad Vaibhav R.*, Dr. Dhobale S.M. and Dr. Gaikwad D.D.

ABSTRACT

The aim of present investigation involved development of an accurate, simple and cost effective UV-spectrophotometric method for estimation of Lovastatin in bulk and in pharmaceutical dosage form. The UV-spectrum showed that maximum absorbance of light was observed at 248 nm and followed linearity in the range of 5-25μg /ml having value of correlation coefficient, 0.9988. This proposed investigation was validated as per ICH guideline Q2 (R1) for linearity, accuracy, precision and recovery. The satisfactory value of percent relative standard deviation for the intraday and inter-day precision indicates that method was precise. Result of the recovery studies (98.73) showed accuracy of method. The investigated method can be used for estimation of lovastatin in bulk and dosage form.

Keywords: The aim of present lovastatin in bulk and dosage form.

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