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All | Since 2019 | |
Citation | 5450 | 3969 |
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FLOATING MICROSPHERES: AN OVERVIEW
Sumita Singh* and Kunal Arora
ABSTRACT This review reveals the importance, efficiency and efficacy of floating drug delivery systems (FDDS). The principal and mechanism of floatation to achieve gastric retention is being discussed in this study. The recent developments of FDDS including the physiological and formulation variables affecting gastric retention, approaches to design single-unit and multiple-unit floating systems, and their classification and formulation aspects are covered in detail. This review also summarizes the in vitro techniques, in vivo studies to assess the performance and application of floating systems, and applications of these systems. These systems are helpful to several problems encountered during the development of a pharmaceutical dosage form. Keywords: Floating drug delivery, Microsphere, Gastric retention, Intragastric. [Download Article] [Download Certifiate] |