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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

FTIR SPECTROSCOPIC METHOD FOR THE QUANTITATIVE ANALYSIS OF TOPIRAMATE IN TABLETS

*P.G. Sunitha, N. Deattu and R. Narayane

ABSTRACT

A rapid FTIR spectroscopic method has been proposed for the estimation of Topiramate in bulk drug and its pharmaceutical dosage form. The method involves the measurement of the area of the infrared band corresponding to the S=O stretching centered at 1049 cm-1. The excipients in the commercial tablet preparation did not interfere with the assay. The linearity range was found to be 100-600 μg /ml. The technique is reliable and useful for quality control for monitoring the adulteration of pure drug. The proposed method is statistically validated and found to be useful for the routine determination of topiramate in tablets.

Keywords: Topiramate, FTIR, Tablets, Validation.

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