Abstract

A REVIEW ON ORALLY DISINTEGRATING TABLETS

B. Deepika*, Kandukoori Naga Raju, Amatul Kabeer, Samrin Begum and K.N.V Rao

ABSTRACT

In terms of formulation, a orally disintegrating tablet (ODT) differ from an conventional tablet by modification of normal disintegrants with a superdisintegrant which is highly sensitive to aqueous environment (saliva) and disintegrates in fraction of time enhancing disintegration followed by immediate dissolution .This unique property helps rapid onset of action, avoid chocking, no water requirement, pleasing mouth feel, avoid first pass metabolism .The present review depicts various aspects of ODT‟s formulation, selection of superdisintegrants, conventional technologies, marketed drugs, evaluation tests.

Keywords: Disintegration, Oral disintegrating tablets, Superdisintegrants.