Abstract

MICROSPONGE DELIVERY SYSTEM: AN UPDATED REVIEW, CURRENT STATUS AND FUTURE PROSPECTS

Namrata Jadhav*, Vruti Patel, Siddhesh Mungekar, Manisha Karpe, Vilasrao Kadam

ABSTRACT

Microsponges are at the forefront of the rapidly developing field of novel drug delivery technology. Microsponge drug delivery technology holds a great promise for reaching the goal of controlled and sitespecific drug delivery and hence, has attracted wide attention of researchers. This article presents a broad review of Microsponges delivery system discussing the principles and preparation methods. Appropriate analytical techniques for characterization of Microsponges like Particle size and its distribution, surface morphology, porosity, density are covered. Advantages, limitations and their possible remedies of the microsponge drug delivery are also mentioned. These microsponges are used in the sunscreens, creams, ointments, over-thecounter skin care preparations, which are meant for topical application. Microsponge drug delivery can provide increased efficacy for topically active agents with enhanced safety, extended product stability and improved aesthetic properties in an efficient and novel manner. They are mostly used for topical use and have recently been used for oral administration.

Keywords: Microsponges, controlled release, porous microspheres, solvent evaporation.