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Abstract

A GREENER APPROACH FOR THE ONE-POT SYNTHESIS OF SUBSTITUTED THIAZOLIDINONES BY USING AN EFFICIENT AND RECYCLABLE IONIC LIQUID

Upendra S. Sisodia*, Seema Khothara and Deepak Swarnkar

ABSTRACT

A convenient protocol for the synthesis of 2,3-diarylthiazolidin-4-one have been achieved by one pot condensation of aryl or heteroaryl amine, aryl aldehyde and 2-Mercaptopropionic acid in 3-butyl-1-methyl-1H-imidazol-3-iumtrifloroacetate as ionic liquid [BMIM][TFA] is described. Reported ionic liquid easy to make, recycle and reuse up to three times in good to excellent yields. Synthesized compounds were fully characterized by their spectroscopic data.

Keywords: Heterocycles, Thiazolidone, Ionic liquid, Green chemistry, One pot synthesis


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