Abstract

EVALUATION OF SYNERGISTIC EFFECT OF ORAL FORMULATION AND TOPICAL APPLICATION OF AYURVEDIC FORMULATION, FOR SKIN HEALTH BENEFITS

Dr. Tanuja Nesari, Dr. Apoorva Sangoram*, Vd. Pooja Pawar, Vd. Trupti Nikam, Vd. Smita Atkalikar

ABSTRACT

Skin health is related to intrinsic & extrinsic factors. Extrinsic factors include environmental & temprature changes, UV radiations, pollution, stress etc. Intrinsic factors are related to genetic predisposition, diseases, diet etc. UV radiation is the most significant factor influencing human skin pigmentation. According to Ayurveda, disruption in complexion (Varna Dusti) includes conditions like Melasma (Vyanga), Mole (Tilakalak), Hyperpigmentation (Karshnya) etc. The management includes Shodhan (Purification of Dosha), Shaman (Pacification of Dosha) & Topical application. The formulations for topical application and internal medication (Shodhan & Shaman) were developed for the present study with the aim to evaluate synergistic effect on Skin Health. The herbs selected in the formulations were authenticated and standardized according to API guidelines. A prospective, randomized, open labelled, parallel study was designed. 75 patients with acne vulgaris were randomized into 3 groups: group A received oral formulation, group B received topical application and group C received combined treatment i.e. oral formulation & topical application for 60 days with dose for Shodhan – 3gm (H.S- after meal), Shaman – 1 gm (BD- after meals) and topical application - as required (H.S.). The outcome measures were assessed using Conventional parameters –Fairness meter scale, Measurement of affected area and photographic evaluation. The results were drawn on the basis of mean ranks and they were compared for groups. The comparison showed that results were significant in group C i.e. synergistic effect of treatment for skin heath. Conclusion – Combined treatment of Shodhan and Shaman medicine along with topical application has synergistic effect was observed in group C.

Keywords: skin health, Shodhan, Shaman, Synergistic effect