Abstract

ANTIOXIDANT ACTIVITIES OF AQUEOUS AND METHANOLIC EXTRACTS OF THE CRAB CHARIBDIS FERIATUS

C. Shibana*, R. D. Thilaga, Jemma Hermelin Jesy Diaz and Esther Elsie

ABSTRACT

The present study has been carried out to compare the free radical scavenging activity of the crab C.feriatus in vitro. The free radical scavenging activity of C.feriatus was accessed by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay using aqueous and methanolic extract in two different concentration. Ascorbic acid was used as standard. The DPPH values were increased in a dose dependent manner. The lowest concentration (250μg/ml) of aqueous extract of C.feriatus was 25.36% and this was increased to 48.28% at 500μg/ml concentration. Methanol extract of C.feriatus possessed higher scavenging activities viz 36.89% and 67.12% at 250 and 500μg/ml concentrations respectively and this was increased with increasing concentrations. The results were compared with ascorbic acid. Result suggests that C.feriatus could serve as a potential source of antioxidants and can be explored as a therapeutic agent in free radical induced diseases.

Keywords: aqueous extract, scavenging activity, antioxidant and C.feriatus.