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ANTI-INFLAMMATORY INVESTIGATION OF KARANJ- OIL ISOLATED FROM PONGAMIA PINNATA (SEEDS) IN EXPERIMENTAL ANIMAL MODELS
Dr. R. K. Singh*
ABSTRACT Pongamia pinnata (L) Pierre Family: Leguminosae (Papiloionoidae) is (Seeds) are used in folk medicine for a treatment of inflammation, arthritis, fever, abdominal colic, inflammation(externally), Alzheimer’s disease and gout. The present study was designed to assess anti- inflammatory activity of Karanj- oil isolated from Pongamia pinnata (Seeds). Karanj –oil of the seeds of Pongamia pinnata (0.1,0.2 and 0.5ml/kg) was found to have significant anti-inflammatory activity against (i) Carrageenin induced (ii) Cotton pellet induced granuloma pouch and (iii) Adjuvant arthritis models in rats. Keywords: Pongamia pinnata: Anti-inflammatory: Carrageenin induced: Cotton pellet induced granuloma pouch: Freund’s adjuvant arthritis: Karanj-oil. [Download Article] [Download Certifiate] |