Abstract

A REVIEW ON BIOLOGICAL STUDIES OF QUINOXALINE DERIVATIVES

Ali Irfan*, Omar Ali Tahir, Muhammad Umer, Sajjad Ahmad and Humaira Kousar

ABSTRACT

Quinoxaline moieties are nitrogen containing heterocyclic derivatives which have broad spectrum biological and pharmaceutical applications. The quinoxaline derivatives are used for the cure of vast range of various diseases. Modifications in structure of quinoxaline substrates have provided applications in various fields and developed remarkable efficacy against diseases with lesser side effects. In this account, glimpses of such quinoxaline derivatives have been presented known for their activity as antiprotozoal, anticancer, antimalarial, antimicrobial antiviral, anti-inflammatory, antidiabetic, anti-tubercular, anti-nociceptive, anthelmintic and as a kinase inhibitor.

Keywords: Bioactive quinoxaline, anticancer, antimicrobial, antineoplastic, anti-inflammatory.