Abstract

STUDY OF NASAL CARRIAGE ISOLATION AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS AMONG HOSPITALIZED PATIENTS, GADHOLI.

Sunil Shekhar Ghimire*, Pooja Singh Gangania, Anu Miglani, V. Singh, Tarsem Kumar

ABSTRACT

Staphylococcus Aureus is a common human pathogen found in skin infections and invasive diseases such as pneumonia, osteomyelitis, endocarditis both in the health care and community settings. Three hundred samples were collected from the patients those were admitted in the Chaudhary Lekhraj hospital India. 240 Staphylococcus Aureus were recovered. HIMEDIAHiCromeMeReSa Agar Base + MeReSa Selective Supplement (FD229) were used in order to detect MRSA, only 60 Methicillin Resistant Staphylococcus Aureus were recovered out of total 80 isolates. Antibiotic susceptibility was tested by using the disk diffusion technique on Mueller-Hinton agar. Almost all the Methicillin resistant Staphylococcus Aureus (MRSA) strains screened from nasal samples were resistant to Methicillin (5μg), Oxacillin (5μg), Cephalexin (30 μg), Gentamycin (50μg), Kanamycin (5 μg), Amikacine (10 μg), Chloramphenicol (10μg), Ciprofloxacin (10μg), Cloxacillin (5μg) Vancomycin (30 μg) and. In, general all MRSA provided were multidrug resistant. The present study signified the emergence of MRSA in the area and also indicates the magnitude of antibiotic resistance in and around the study area. The major cause of this may be unawareness and indiscriminate use of broad-spectrum antibiotics. Our study revel the presence of MRSA in the Chaudhary Lekhraj hospital this might also be prevalent in other parts of India as antibiotic misuse is equally common there. This will help in treating this problem in referral hospitals.

Keywords: Staphylococcus Aureus, MRSA (Methicillin resistant Staphylococcus Aureus), Antibiotic.