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Abstract

PHARMACOLOGICAL EVALUATION FOR ANTI-FERTILITY ACTIONS OF AILANTHUS EXCELSA IN WISTAR ALBINO RATS

Munesh Mani*, Ashish Kumar Sharma and G.S. Chakraborthy

ABSTRACT

The present study was aimed to evaluate the anti-fertility activity of root bark of Ailanthus excelsa. On the basis of traditional use and literature reference, this plant was selected for antifertility activity. Root bark is traditionally used as anti-fertility agent. Anti-fertility activity of methanolic extract of root bark of Ailanthus excelsa were evaluated at three doses i.e. 100mg/Kg, 150mg/Kg and 200mg/Kg of the body weight of the rat and observed that treatment with methanolic extract of Ailanthus excelsa at the dose of 200 mg/kg was shown significant anti-fertility effect. Ailanthus excelsa posses anti-fertility activity by inhibiting implantation and abortifacient action.

Keywords: Antifertility, Ailanthus excelsa, implantation, abortifacient.


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