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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

DEVELOPMENT AND CHARACTERIZATION OF MUCOADHESIVE DRUG DELIVERY SYSTEM CONTAINING LIPOSOMES

Sayli S. Salaskar* and Rachel Geevarghese

ABSTRACT

Sodium Cromoglycate is a Drug used for treatment of vernal kerato conjunctivitis. Aim of study is to formulate mucoadhesive drug delivery system containing liposomes to improve and sustain drug delivery to eye as compared to marketed eye drops. Multilamellar vesicles (MLVs) were prepared by using phospholipid 90H and cholesterol in different ratios by film hydration method. Liposomes were then characterized for entrapment efficiency, Particle size and zeta potential. Prepared liposomes were then incorporated in an in situ gel containing carbopol 940 and HPMC K15m. This system was then tested for drug release, gelling capacity, residence time, viscosity, drug content, isotonicity. Effect of autoclaving was studied considering liposomal integrity. Acute Irritation studies were carried on Albino Rabbits.

Keywords: liposomes, In Situ gel, Draize test.

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