Abstract

A REVIEW ON RP-HPLC OF NSAIDS

Zoha Siddiqua* and S. Mohammed Noorullah

ABSTRACT

Pharmaceutical Analysis plays a major role today, and it can be considered as an interdisciplinary subject. Drugs and Pharmaceuticals are chemicals or chemical-like substance which might be organic, inorganic or any other origin. Whatever might be the origin, we use some property of these drugs to measure them qualitatively and quantitatively. Analytical method development and its validation is an important aspect in drug discovery process. Development of analytical method producing accurate and precise data is necessary to ensure the quality and safety of the drug. In today’s scenario, the most common analytical method employed for estimation of drugs is Reverse Phase High Pressure Liquid Chromatography (RP-HPLC) because of its high sensitivity and speed. Many types of analytical methods are available for estimation of Non-Steroidal Anti-inflammatory Drugs (NSAIDs) including RP-HPLC. This review article briefly discusses analytical methods available for the estimation of currently available Non Steroidal Anti-inflammatory Drugs (NSAIDs) specifically focusing on RP-HPLC.

Keywords: NSAIDS, Analytical methods, RP-HPLC, analysis of NSAIDS, Non Steroidal Anti-inflammatory Drugs