STUDIES ON THE NEPHROPROTECTIVE AND NEPHROTOXICITY EFFECTS OF ETHANOLIC EXTRACT OF CYMBOPOGON CITRATUS (LEMON GRASS) ON WISTAR ALBINO RATS
Adegbegi J. Ademuyiwa*, Seyifunmi O. Elliot, Komolafe Y. Olamide, Akintemi A. Omoyemi and Oluwayomi S. Funmi
ABSTRACT
Reactive oxygen species and free radicals are involved in the nephrotoxicity induced by both synthetic and medicinal drug. The nephroprotective and nephrotoxicity effects of ethanolic extract of Cymbopogon citratus (200mg/kg, 500mg/kg, 1000mg/kg, 2000mg/kg, 4000mg/kg and 5000 mg/kg) administration was investigated for oxidative renal damage in albino rats. In the determination of the effects of graded dosages ethanolic extract of Cymbopogon citratus on the creatinine, total protein and albumin levels, no significant (p
Keywords: Reactive oxygen species; Nephrotoxicity; Cymbopogon citratus; kidney; Haematological parameters; Histopathology.
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