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THE THERAPEUTIC EFFECT OF PURSLANE (PORTULACA OLERACEA) EXTRACT ON WOUND HEALING IN DIABETIC ALBINO RATS
Shaimaa M. Eldeighdye*, Abdel-Khalek L.G., Taha M.S., T. M. Allam, Hassanian W.F., Akaber T. Keshta and A. El Farargy
ABSTRACT
wound healing is common complication of diabetes. The hyperglycemic state and the poor blood supply in diabetic patients interrupts appropriate wound healing and may lead to microbial infection and gangrene formation. Purslane possesses mucilaginous substances which known for their antioxidant, antimicrobial and increasing the tensile strength of the skin. present study has design with the objective, to investigate whether the ethanolic extract of Purslane would accelerate the impaired wound healing in diabetic rats. Also, to assess its impact on liver function in induced diabetic rats. Diabetes was induced in 3groups of rats by administration of STZ-nictonamide (60,140 mg/Kg b.w) respectively. Topical treatment with (40 mg/250 mm2 wound) Purslane Keywords: Wound healing, Portulaca oleracea, Streptozotocin, Excision wound model. [Download Article] [Download Certifiate] |