Abstract

SYNTHESIS, CHARACTERIZATION AND REGULATORY ASSESSMENT OF SCHIFF’S BASES USING ALUM [KAI (SO4)2.12H2O] AS AN EFFICIENT AND NOVEL CATALYST

Ansar R. Shaikh, Raje Shaikh B. B. and Mazahar Farooqi and Syed Abed*

ABSTRACT

Herein we report, Synthesis, Characterization and Regulatory Assessment of Schiff’s bases using alum as a novel catalyst. Alum [KAI (SO4)2·12H2O] performs as a novel catalyst for the synthesis of Schiff’s bases from 6-methoxy naphthalene 2-carbaldehyde with various substituted amines in good to excellent isolated yield (65–89%) using ethanol as a solvent at ambient temperature. Several solvents were examined for this reaction; however, in terms of reaction yield and time, ethanol was found to be the optimum solvent. The remarkable advantages offered by this method is an inexpensive and easily available catalyst, a simple procedure, mild reaction conditions and faster the reactions. The structures of synthesized compounds elucidated using Mass Spectometry and 1H NMR spectroscopy.

Keywords: Schiff’s base, Alum, Amines, Regulatory Assessment.