Abstract

ASSESSING THE POTENTIAL OF THE ETHANOLIC EXTRACTS OF TERMINALIA CHEBULA AGAINST BREAST CANCER

Deena Priscilla, Dr. R. Jasmine*

ABSTRACT

A screening conducted on plants that have potential as anticancer is a promising way for discovering novel chemotherapeutic compound. The anti-proliferative effects of ethanolic extract of Terminalia chebula have been studied on MCF-7 type of cell lines by MTT assay. In this study, extracts of T chebula has been used to test the cytotoxic effects on breast cancer cells. The study with the ethanolic extracts of the plant displayed cytotoxic effects on MCF-7 cells. Current study investigates the anticancer activity of the ethanolic extract of T chebula fruits in breast cancer (MCF-7) cell lines ex vivo. Results of MTT assay suggested that the ethanolic extract of Terminalia chebula can induce cytotoxicity in cancer cells, irrespective of origin, in a concentration- and time-dependent manner. Our analysis have yielded positive and promising results that has paved way for further progress in our research. It is evident that we could develop a better drug to combat cancer from natural sources.

Keywords: Anticancer, Terminalia chebula, Phytotherapy, Breast cancer, MCF-7.