Abstract

COMPARISON OF SWERTIAMARIN CONTENT IN DIFFERENT ANTIDABETIC HERBAL MARKETED PREPARATION CONTAINING ENICOSTEMMA LITTORALE

Jayshil Bhatt*, Rajshwaree Rathod, Vinod Jairaj and Ramesh Goyal

ABSTRACT

Swetiamarin is one of the phytoconstituents present in Enicostemma littorale Linn. which is known for its hypoglycemic activity from ancient times. In our previous studies we have reported new HPLC menthod of analysis of swertiamarin in herbal preparations containing E. littorale. In the present study we have utilized this method for standardization of marketed formulations of E.littorale using swertiamarin and compared with the one formulated in our laboratory. This HPLC method was found to be reproducible, accurate and precise and could detect swertiamarin concentration at microgram level. The developed HPLC method would be an important tool in the way of acceptability of quality control method of polyherbal formulations. Swertiamarin was found to be in the range of 0.5mg per pills with the highest amount of found in cold extract prepared by lyophilisation(1.2mg) and in Saptarangiadi Pills (3.3mg/pills).

Keywords: Swetiamarin in herbal preparations containing E. littorale.