Abstract

OXIDATION OF L-LEUCINE BY TRIBUTYL AMMONIUM CHLOROCHROMATE IN ACID MEDIUM: A KINETIC AND MECHANISTIC STUDY

Sayyed Hussain, Prabhkar Kute*, Sayyed Salim and Mazahar Farooqui

ABSTRACT

The kinetics of oxidation of L-leucine by Tributyl Ammonium Chlorochromate (TriBACC) was studied spectrophotometrically at 445 nm. The reaction between L-leucine and (TriBACC) in acid medium exhibits 1:1 stoichiometry. The rate of reaction was first order with respect to H+ and less than unit order with respect to L-leucine and inverse first order depends on (TriBACC). The effect of ionic strength was investigated. The main product was identified as the corresponding carbonyl compound. The rate constant as a function of temperature (303-323 K) were used to calculate activation parameters of the oxidation of L-Leucine by (TriBACC). A plausible mechanism was proposed to explain the results of kinetic studies.

Keywords: kinetics, L-leucine, tributylammonium chlorochromate, oxidation, mechanism.