DEVELOPMENT AND VALIDATION OF UV-VISIBLE SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF SELECTED ANTISEPTIC DRUG IN BULK AND PHARMACEUTICAL DOSAGE FORM
Rushikesh J. Lohar*, Vipul M. Patil, Ravindra G. Gaikwad, Shitalkumar S. Patil
ABSTRACT
The present study describes a simple, accurate, precise and sensitive UV-Vis spectrophotometric method for determination of Octenidine Dihydrochloride in pure and pharmaceutical dosage form. The measurement of absorbance at two wavelengths, 285nm, λ max for Octenidine Dihydrochloride respectively. The Beers law observed in the concentration range of 10-100μm/ml with correlation coefficient 0.998 respectively. The method was validated for several parameters like accuracy, precision and linearity. The values of relative standard deviation and % recovery were found to be satisfactory, indicating that the proposed method is precise and accurate and can be used for the determination of Octenidine Dihydrochloride in pure drug and pharmaceutical dosage form.
Keywords: Octenidine Dihydrochloride, UV-Visible spectrophotometry.
[Download Article]
[Download Certifiate]