Abstract

PHYTOCHEMICAL SCREENING AND BIOLOGICAL ATIVITIES OF IMPATIENS BALSAMINA. L SEEDS

Shivaji Bole*, Shivakumara, Seitajit Singh Wahengbam, Naveen kumar Rana,Swarnava Kundu, Siddharth Dubey, Vedamurthy AB

ABSTRACT

In vitro antioxidant, antidiabetic, anti-inflammatory activity and phytochemical evaluation of solvent extracts of seed of Impatiens Balsamina. L. was analyzed. Phytochemical screening of the ethanolic extracts of seeds revealed the presence of alkaloids, flavanoids, terpenoids, tannins and saponins. Antioxidant activities of these extracts were evaluated by in vitro antioxidant assay models like DPPH, reducing power assay and phospho-molybdenum method. antidiabetic activity was evaluated by amylase inhibition assay method and anti-inflammatory activity was determined by induced protein denaturation method. The Results obtain in this study showed that the seeds of Impatiens Balsamina. L has antioxidant, antidiabetic and antiinflammatory activity which provide a basis for traditional use of medicinal plant. IC50 value was calculated for both antioxidant and anti-inflammatory activity and was found to be 320μG/mL. and 210 μG/mL. respectively.

Keywords: Antioxidant, Antidiabetic, Anti-inflammatory, BSA Denaturation.