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HISTOPATHOLOGICAL STUDIES ON ADENOHYPOPHYSIS OF FRESH WATER FISH GLOSSOGOBIUS GIURIS (HAM)
*Narayanaswamy S. Y. and M. Ramachandra Mohan
ABSTRACT Histopathology of the adenohypophysis was observed during spawning phase, the fish G. giuris on treatment with sub lethal concentrations of Neem oil (0.05 ppm, 0.25 ppm and 0.5 ppm) for 24, 48, 72 and 96 hrs intervals. The results of the present study showed morphological changes in the cell structure. The PRL cells showed decrease in their numbers and size with an increase in the concentration of neem oil. During 24-96 hrs treatment, PRL cells showed continuous degranulation and vacuolization in the cytoplasm with conspicuous intercellular spaces. Prolactin cells in the RPD showed loosely arranged with less granules and the intercellular spaces were predominant with a decrease in the mean nuclear diameter. Investigation on Gonadotrophs – GTH cells showed degranulation and hypertrophy of cells and nuclei after the fishes were exposed for 24 hrs neem oil on treatment. In higher concentration of neem oil treatment (0.5 ppm for 24 hrs), the GTH showed various stages of degranulation which were distributed sparsely. A reduction in the number and diameter of the gonadotrophs indicate possible reduction in release of gonadotrophs. Keywords: Neem oil, G.giuris, Prolactin(PRL) and Gonadotrophs (GTH). [Download Article] [Download Certifiate] |