SCREENING OF GANODERMA TSUGAE FOR ANTIMICROBIAL ACTIVITES
Sakthivigneswari Ganesan and * K.Dharmaraj
ABSTRACT
Mushrooms have increasingly being explored as a valuable source of
nutrients’ and highly bioactive secondary metabolites. Ganoderma
tsugae is used as an elixir of life to promote health and longevity in
East Asian countries. It reported as therapeutic foods that are useful
in preventing diseases such as hypertension, hypercholesterolemia
and cancer. Ganoderma tsugae was collected in our College Campus
during rainy season. Further the powder of Ganoderma tsugae was
used by antimicrobial activity was evaluated against Escherichia coli,
Pseudomonas aeruginosa, Staphylococcus aureus and Klebsiella
pneumoniae. Acetone, ethanol and methanol used as extractive
solvents. Maximum antibacterial activity of crude extracts of methanol
extracts Ganoderma tsugae (20mm ± 0.577mm) shows high level of
antibacterial activity against Escherichia coli. Acetone and ethanol
extracts shows good antibacterial activity (17± 0.666mm, 18± 0.577)
against Klebsiella pneumoniae and Escherichia coli respectively. Gram negative bacteria
such as Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae were most
susceptible than the gram positive bacteria (Staphylococcus aureus). The zones of inhibition
in both the extracts are less than the methanolic extracts against the pathogens.
Keywords: Ganoderma lucidum, Escherichia coli, Pseudomonas aeruginosa,
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