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Citation | 5450 | 3969 |
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LINKING DRUG ACTION WITH PATHOPHYSIOLOGY OF ALZHEIMER’S DISEASE
*Ibel Chiramel Fredy and Princy Louis Palatty
ABSTRACT
Background: Alzheimer’s disease has been characterised and the etiopathology unravelled new concept and aspect that were hitherto unknown. Areas of focus: drug therapy of Alzheimer’s disease has undergone a radical change with the incoming of hordes of drugs with novel mechanism. Common drugs included are Disease Modifying drugs (anti-amyloid agents, tau based therapy, glial cell modulators), Anti-oxidants etc. Despite the availability, efficacy and safety remains to be seen. Conclusion: Despite, a wide variety of drugs available for the treatment of Alzheimer’s disease the efficacy, Quality Of Life and safety is still suboptimal. Keywords: Alzheimer’s Disease, Anti-amyloid agents, Tau based protein, Pathophysiology [Download Article] [Download Certifiate] |