Abstract

PRELIMINARY PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF FRONTAL LEAVES OF TECTONA GRANDIS (FAMILY: VERBENACEAE)

K. Krishnananda Kamath* and A. Ramakrishna Shabarya

ABSTRACT

Tectona grandis (Teak) is widely used as folk medicine in India for its pharmacological relevance. It is used in the treatment of various skin diseases and diarrhoea. Based on the morphological studies, frontal leaves authentication was done. Results of physicochemical parameter reveal that significant amount of acid insoluble ash has been detected, which indicates presence of various silica materials. Phyto-chemical screening studies on extracts revealed the presence of alkaloids, tannins, flavonoids and saponins. These constituents have been reported to possess antibacterial activities. To study the antibacterial activity, extracts of concentrations of 25, 50, 75, and 100 mg/ml were used against bacterial strains by using agar well diffusion method. The selected organisms are Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa which are the common causes for infections in patient with burns, and other types of wounds. Activity was observed at a concentration of 50-100 mg/ml. These results reveals that frontal leaves of T. Grandis have potential for the treatment of wounds and burns, further pharmacological study on animals and formulation of proper dosage forms are essential.

Keywords: Tectona grandis, Phytochemical, Antibacterial activity.