Abstract

DENGUE THE BREAKBONE FEVER: PATHOPHYSIOLOGICAL AND PHARMACOTHERAPEUTIC UPDATE

Amit Gangwal*, Jacky Dumbwani, Virendra Sanoniya, Namrata Rathore, Sanjay Jain

ABSTRACT

Dengue, also known as dengue hemorrhagic fever, is the most common mosquito-borne viral disease of humans that in recent years has become a major international public health concern and is becoming fatal day by day as cases of dengue are surfacing in India. Although the sciences has took long strides in many domain but it has yet to address some mysteries. Globally, 2.5 billion people live in areas where dengue viruses can be transmitted. The geographical spreads of both the mosquito vectors and the viruses have led to the global resurgence of dengue fever. All four types of the dengue viruses are re-emerging worldwide and causing more frequent epidemics. In this review article an attempt has been made to crawl highly relevant information pertaining to pathophysiology and current option (though limited) to manage and treat dengue.

Keywords: Dengue, symptoms, papaya, mosquito, breakbone fever, virus.