Abstract

ANTIOXIDANT ACTIVITY OF ACTINOMYCETE ISOLATES FROM MARINE SAMPLES

G. V. Phani Bhushan*, G. Girija Sankar, T. Prabhakar, P. V. Kamala Kumari

ABSTRACT

Marine organisms are still largely untapped source and hold tremendous potential in the search and discovery of novel bioactive compounds. Because of the immense biological diversity in the sea as a whole, it is increasingly recognized that many new chemical compounds exist in the oceans. It has been reported that only 1% of the marine microorganisms have been explored. Marine actinomycetes are a virtually unlimited source of novel chemical structures with many potential therapeutic applications. Their property that most excites the interest of biotechnologists and microbiologists are the ability to produce a very diverse range of metabolic products, some of which have important roles in medicine. The genus Streptomyces is known to produce a large number of bioactive molecules. In the present study marine samples were screened for the isolation of actinomycetes. A total of 45 marine samples were screened and 68 actinomycetes were isolated. By eliminating the isolates which are identical, 58 isolates were finally selected. The isolates were screened antioxidant activity by DPPH radical scavenging method. Two isolates (PWS 3/1 and 53) exhibited significant antioxidant activity.

Keywords: Streptomycetes, Antioxidant, DPPH Radical Scavenging.