Abstract

PREVALENCE OF GLUCOSE AND CHOLESTEROL DYSREGULATION IN PSYCHIATRIC PATIENTS TAKING TYPICAL OR ATYPICAL ANTIPSYCHOTIC DRUGS

Dr. C. I. Sajeeth, Dr. Gayathri V., Dr. Vini Pavithran, Manu Prasad P.*, Krishnendhu B., Haritha S. B. and Akshara S. Kumar

ABSTRACT

According to world health organization one in four person are suffering from some sort of psychiatric conditions. Most of the antipsychotics induce certain metabolic abnormalities but in majority condition the benefit outweigh the risk, so the aim of the study is to estimate the prevalence or proportion of patients suffering from various metabolic disorders after initiating the antipsychotic therapy. The study procedure include dividing the subjects into two groups, patients taking atypical as well as typical antipsychotics and conducted over a period of five months. Various metabolic parameters like blood glucose and cholesterol level were monitored for minimum of three follow-ups and determined the average rise in these parameters. The study result was women’s between the ages 40 – 60 are more prone to develop metabolic disorders than males after the antipsychotic therapy, the reason behind this abnormal rise mainly depends on the hormonal imbalance i.e. estrogen, prolactin.

Keywords: Antipsychotics, metabolic syndrome, dyslipidemia, schizophrenia.