Abstract

SYNTHESIS, ANTIMICROBIAL SCREENING STUDIES OF SOME TERPOLYMER RESINS DERIVED FROM 2,4- DIHYDROXYPHENYL ALKYL KETONE, MELAMINE AND FURFURAL

Maroju Ravi Chandra*, Budarapu Neelamma, Bathini Chandra mouli and Devanapelly Shashikantha Rao

ABSTRACT

Antimicrobial activity of a series of new resins materials synthesized from substituted resorcinols by reaction with melamine using furfural as condensing agent in the presence of various acids and bases as catalyst evaluated against Escherichia coli, Proteus vulgarism, Bacillus substillis, Staphylococcus and antifungal activity against Drecherahalodes, Fusarium oxysporium. It is found that some copolymer resins were toxic at one or the other concentration. Within the copolymer resins, furfural based resins were highly active against both the fungi and caused total germination inhibition at 960 g/ml under investigation. Both the pathogens were equally sensitive to the copolymer resins parachlorophenyl substituted based copolymer resin is more active than other resins. Similarly, acid catalyzed terpolymer resins were found to be more potent than base catalyzed resins. The structures of resins were characterized by FTIR, 1H NMR spectra. The solubility and physicochemical properties of resins were investigated.

Keywords: Substituted resorcinol, melamine furfural resins and antimicrobial agents.