Abstract

REVIEW ON NEEDLE FREE DRUG DELIVERY SYSTEM

P. Raghuveer*, D. Madhuri and Maddumala Rajeswari

ABSTRACT

Needle free injection systems are innovative ways to introduce a variety of medicines in patients without piercing the skin with a traditional needle. These systems work by the mechanism in which liquid medication is forced at an elevated speed through a small orifice that is held against the skin. Due to this an ultrafine stream of high pressure fluid is created, that penetrates the skin devoid of the use of a needle, thus faster administration of drug occurs as compared to conventional needles. Needle free systems are designed to solve the problems created due to conventional needles making them safer, less expensive and more suitable. It is expected that these systems will augment the rate of vaccination and reduce the amount of antibiotics prescribed. Moreover, they should decrease the occurrence of needle stick accidents that have been seen in some health care workers contracting diseases. Today, they are an increasingly rising technology that promises the administration of medicine efficient with reduction of pain. Companies are not only working on developing technologies that are safer and easier to use, but also on alternatives which can deliver more types of medicines.

Keywords: Needle free injection devices, Powder based NFI, Liquid based NFI, Needle free devices, Microjets.