Abstract

A FT-IR SPECTROSCOPIC STUDY ON ALANGIUM SALVIFOLIUM LINN. SEED OIL

*Dr. Poonam Sharma, Anurag Mishra, Dr. Ajay Kumar Sharma, Prof. K. N. Dwivedi

ABSTRACT

The seeds of Alangium salvifolium Linn. have been traditionally reported to exhibit a variety of biological activities, including antidiabetic, anticancer, anti-inflammatory, antimicrobial activities. The objective of this study was to verify the traditional claims and to evaluate the oil prepared from seeds of Alangium salvifolium to screen the antidiabetic, anti tumour and anti-inflammatory activities and the mean by which wound heals. FT-IR study shows the presence of flavonoids, tannins, methyl, polysaccharides, and amide groups. Flavonoids have anti-inflammatory and antioxidant activity, tannins have anticancer, antidiarrhoeal activities and improve intestinal disorder. Presence of methyl groups have activity on DNA and switch off to the cancer causing oncogenes. Polysaccharides have immune – modulating activity, anticoagulant, hypoglycaemic and antiviral activity. The results of present study verified the traditional claims made by Ayurvedic practitioner. However, the chemical constituents responsible for the pharmacological activities remain to be investigated.

Keywords: Antidiabetic, Anticancer, Anti-inflammatory, Oncogenes.