SOLUBILITY ENHANCEMENT BY VARIOUS TECHNIQUES: AN OVERVIEW
*Mohini S.Patil, Sheetal Z.Godse, Dr. R. B.Saudagar
ABSTRACT
Solubility is not to be confused with the ability to dissolve or liquefy a
substance, since this process may occur not only because of dissolution
but also because of a chemical reaction. Low aqueous solubility is the
major problem encountered with formulation development of new
chemical entities as well as for the generic development. More than
40% of new chemical entities developed in pharmaceutical industry are
lipophillic and fail to reach the market due to their poor water
solubility. The solubility behavior of drug is the major challenge for
formulation scientist. The present review is devoted to increase the
solubility of poorly water soluble drugs.
Keywords: Solubility Enhancement, BCS Class.
[Download Article]
[Download Certifiate]