Abstract

PHYTOCHEMICAL STANDARDIZATION OF AAVARAI KUDINEER FORMULATION (AKF) - AN OFFICIAL SIDDHA POLY HERBAL FOR DIABETES MELLITUS

G. Prakash Yoganandam*, V. Gopal and J. Thanka

ABSTRACT

The Siddha system of medicine is a traditional Indian system of medicine. Among the various Siddha formulations useful in the treatment of diabetes mellitus, “Aavarai Kudineer Formulation” (AKF) is a reputed formulation. This formulation is scientifically under explored in the field of Phytochemistry. Hence an attempt was made to scientifically standardize the AKF under Phytochemical parameters. Phytochemical evaluation such as preliminary phytochemical screening, fluorescence analysis, TLC and HPTLC studies were performed for the first time in this formulation. The information obtained from preliminary phytochemical screening and fluorescence analysis for seven individual drugs as well as AKF would be useful in finding out the genuineness of the drug. TLC studies of individual drug was compared with AKF in the newly developed solvent system: Toluene: Ethyl acetate: Methanol: Water (9.5: 5: 0.7: 0.9) and number of spots are observed under UV254nm and UV365nm. HPTLC Qualitative analysis of AKF shows different peaks scanned under UV254nm and UV365nm. The results of these investigations could, therefore, serves as a basis for proper identification, authentication and standardization of the AKF.

Keywords: Aavarai Kudineer, Siddha system of medicine, Diabetes mellitus, Phytochemical evaluation.