Abstract

EFFECT OF MEDICINAL PLANTS AGAINST MULTI-DRUG RESISTANT PSEUDOMONAS AND KLEBSIELLA SPECIES

Rahul Rajendra Shelke* and Meera Chavan*

ABSTRACT

Multi-Drug resistant organisms are resistant to one or more therapeutic classes of antimicrobial agents. The number of multi drug resistant organism are able to spread from person to person. Today’s most problematic multi drug resistant bacteria are Klebsiella pneumoniae and Pseudomonas aeruginosa. Four medicinal plants were selected to determine the antimicrobial potential against multi drug resistant Pseudomonas species and Klebsiella species. MDR positive clinical sample was collected from pathological lab. In all total, four Pseudomonas species and four Klebsiella species were isolated. Their identification and antimicrobial sensitivity was tested on VITEK 2 machine. In the present study, it is clearly observed that Azadirachta indica and Adhatoda vasica was found to be the most effective against all these isolated multi drug resistant Pseudomonas species and Klebsiella species but most of these species are resistant to Bouhinia racemosa. The antimicrobial potential of plant extracts was determined by agar well diffusion assay. Adhatoda vasica showed the highest zone diameter against these multi drug resistant bacteria.

Keywords: Multi Drug Resistant, Antimicrobial activity, VITEK 2, Medicinal Plants.