Abstract

A PROSPECTIVE STUDY ON PRESCRIBING PATTERN AND DRUG-INTERACTIONS IN TYPE 2 DIABETES PATIENTS WITH COMORBID CARDIO COMPLICATIONS IN A TEACHING HOSPITAL

Pavan Gara*, Md. Imran, George M. Varghese, Arun J., Basavaraj K. Nanjwade

ABSTRACT

The study involves screening the prescription trends in type 2 diabetes mellitus patients with comorbid complications imposed with diabetes. However study was undertaken in the Oxford medical college and hospital Bangalore, to evaluate prevalence rate of type II diabetes mellitus in males and females as well drug–drug interactions comprise to be potential & actual appropriateness which deserve clinical attention and choice of prescribing pattern promoting rational use of medications. The study was Simple Prospective observational study which was carried out for a period of six months 200 cases were collected in the study which determines number of OADDS therapy were administered for type II DM patients ruling out generic or essential drug prescribing, monitoring prominent drug interactions, drug safety management. The results were analyzed Maximum numbers of patients were in the age group of above 60 years (95.70%) and among 200 cases, males constituted 106 (57%) and females 94 (47%). Out of 200 patients 112 patients (66.27%) patients were found suffering with co morbid concurrent illness hypertension followed by cardio complications associated (HTN-IHD, HTN-CAD, OTHER COMORBIDITIES). Essentially assessment of therapy and management of disease with combination therapies of insulin and different oral anti-diabetic drugs were prescribed for proper glycemic control. As well clinical attention on drug interactions by clinical pharmacist interventions indicates clinical effectiveness of therapy is influenced by prescribed agent selection and therapy changes as well patient’s adherence with drug regimens.

Keywords: Prescribing pattern, rational therapy, Drug interactions, Generic use, Comorbidity.