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SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF PYRAZOLINE DERIVATIVES DERIVED FROM CHALCONE
Falguni G. Bhabhor and Harish R. Dabhi*
ABSTRACT A Chalcone was prepared by the reaction of 4-acetyl-5-methyl-2-(4- methylphenyl)-2, 4-dihydro-3H-pyrazole-3-one with different substituted aldehydes. Treatment of this Chalcone with hydrazine hydrate afforded the corresponding pyrazoline in good yields. All the new compounds have been characterized by IR, 1H-NMR, GC-MS and element analysis. The antibacterial activity of these compounds was determined with the reference of standard drug. Keywords: Chalcone, Pyrazoline, Antibacterial activity. [Download Article] [Download Certifiate] |