Abstract

SOME ENZYMATIC ACTIVITY IN SERUM WITH CHRONIC RENAL FAILURE

Prof. Tareqc Y. Ahmed and *Lana A. Mansur

ABSTRACT

The research was concerned with measuring the activity of the following enzymes: Paraoxinase (PON1), proilase (PRO), aryl esterase (Ary), Lactonase, Glutathion – Stransferase (GsT), polymine oxidase (PAO), Glucoolatonase (GIN), Nitric oxide (NO) and Superoxide dismutase (SOD), in serum with chronic renal failure (CRF) undergoing hemodialysis, seventy nine patients with CRF before heomdialysis and eighty healthy controls were in clouded in this study. Two groups of CRF patients and healthy subjects were divided according to age (20 – 40) and (40 – 65) respectively. The result showed a significant decrease in serum PONI, Ary, Lactonase (Lac), GIN, NO, SOD, ADA activities in CRF patients while PAO, GST increase significantly in serum patients compared to normal individuals.

Keywords: PONI, PR, Ary, Lactonase, GST, PAO, ADA, NO, SOD, CRF.