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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

FAST AND SENSITIVE HPLC METHOD FOR THE DETERMINATION OF ZOLPIDEM IN BULK AND FORMULATION

S.V.V. Dhanu Radha*, K.M. Ch. Appa Rao and K. Rama Krishna

ABSTRACT

A simple, rapid, accurate, precise method has been developed for the estimation of Zolpidem in bulk and formulation using reverse phase high pressure liquid chromatography. The method was developed on C18, HYPERSIL250 mm length, 4.6 mm inner diameter column in an isocratic mode using mobile phase containing a ternary mixture of ammonium acetate, methanol and acetonitrile. (30:45:25, v/v/v) The flow rate and detection wavelength were 1.0ml/min and 248nm respectively. The retention time of the drug was found to be 3.05min and the method produced was linear in the concentration range of 30-90 μg/ml.

Keywords: Benzodiazepines, Zolpidem, HPLC, Ammonium acetate and Acetonitrile.

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