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Abstract

INVITRO ANTICANCER ACTIVITY OF LEAVES AND STEM OF AZIMA TETRACANTHA LAM.

Nandhini Sundaresan*, Ramalingam Radha and Periyannan Muthusamy

ABSTRACT

The present study deals with anticancer activity of Azima tetracantha. The leaves and stem of the plant material were extracted with hexane and ethanol using soxhlet extraction. Anticancer activities of various extracts were assayed with standard MTT colorimetric procedure against MCF-7 cell lines. From the analysis it was found that ethanolic leaf extract of Azima tetracantha showed MCF-7 cell line inhibition at ng range tested dose and other three extracts (hexane - leaf, stem and ethanolic stem) also displayed anticancer activities against MCF-7 cell line. Further work is in progress to evaluate the chemical constituents present in the extract.

Keywords: Azima tetracantha Lam., Antioxidant, Anticancer, MTT Assay, MCF-7 cell lines.


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