INVITRO ANTICANCER ACTIVITY OF LEAVES AND STEM OF AZIMA TETRACANTHA LAM.
Nandhini Sundaresan*, Ramalingam Radha and Periyannan Muthusamy
ABSTRACT
The present study deals with anticancer activity of Azima tetracantha.
The leaves and stem of the plant material were extracted with hexane
and ethanol using soxhlet extraction. Anticancer activities of various
extracts were assayed with standard MTT colorimetric procedure
against MCF-7 cell lines. From the analysis it was found that ethanolic
leaf extract of Azima tetracantha showed MCF-7 cell line inhibition at
ng range tested dose and other three extracts (hexane - leaf, stem and
ethanolic stem) also displayed anticancer activities against MCF-7 cell
line. Further work is in progress to evaluate the chemical constituents
present in the extract.
Keywords: Azima tetracantha Lam., Antioxidant, Anticancer, MTT Assay, MCF-7 cell lines.
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