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Abstract

ANTI-CANCER ACTIVITY OF CARDIOSPERMUM HALICACABUM LINN. LEAF EXTRACTS AGAINST HEPATOCELLULAR CARCINOMA CELL LINE (Hep-G2)

Rajesh S., Sivakumari K.*, Ashok K. and Abitha A. R.

ABSTRACT

Cancer is most dangerous diseases in the world. The objective of the research is to explore the phyto-constituents present in the aqueous, chloroform and methanol extracts of C. halicacabum leaves. To investigate the anti-cancer potential of the all three leaf extracts of C. halicacabum against Hep-G2 cell line. To identify the apoptotic effect of leaf extracts against Hep-G2 cell line by propidium iodide staining method. GC-MS study of the leaf extract having higher activity.

Keywords: C. halicacabum, phytochemical screening, MTT assay, propidium iodide staining, GC-MS, Hep G-2 Cell line.


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