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Abstract

THE EFFECT OF VARYING CONCENTRATIONS OF SAMBONG LEAVES (Blumea balsamifera) DECOCTION ON WOUND HEALING

Krishna Deo Das, Satyam Prakash* and Khushbu Yadav

ABSTRACT

Background: Blumeae balsamifera (Sambong) is an ancient medicinal herb with a rich constituents of essential oils and widely used in the Philippines for a long period of time before the introduction of modern medicine for the treatment of septic wounds and other infections. The dominance of commercially manufactured products is increasing day by day due to the rapid development and progress. Drugs are first and foremost need to cure ailments and different diseases for human beings. Almost all the country has always been dependent on highly priced commercial drugs giving little chance for the utilization of locally grown medicinal herbs and plants. Therefore, the present study was focussed to determine the effect of Blumea balsamifera on wound healing as an alternative to expensive medicine such as betadine. Methods: The descriptive method was used to find out the active constituents of the Sambong leaves through phytochemical screening whereas experimental method was used to determine the characteristics of the experimental mice for their treatment of wounds using Sambong leaves decoction. Results: The treatments with 50, 100 and 150 grams of Sambong leaves decoction in all three replications range from 11-12, 7-9 and 5-6 days for deep wound which was found fair, good and very good respectively and with betadine from 3-4 days was very good to excellent as positive control. The effect of Sambong leaves decoction and betadine in the number of days and redness and swelling of wound healing in mice was found to be statistically insignificant. Conclusion: The varying concentrations of Sambong leaves decoction produce different effect on deep wounds of mice. The greater the concentration of Sambong leaves decoction, the faster the wound healing was ensured.

Keywords: Wound healing, Blumea balsamifera, Phytochemistry, Betadine, Decoction.


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