Abstract

FOUR SYNTHESIS METHODS OF SCHIFF BASE LIGANDS AND PREPARATION OF THEIR METAL COMPLEX WITH IR AND ANTIMICROBIAL INVESTIGATION

*Dr. Kapadnis Kailas H., Jadhav Sheetal P., Dr. Patil Anita P., Dr. Hiray Apoorva P.

ABSTRACT

A Schiff base [(E)-N1-(4-Chlorobenzylidene) benzene-1,3-diamine] are synthesize by Microwave irradiation, Reflux, Stirring and Grinding methods. Compared with all this method of synthesis of Schiff base ligand the Microwave irradiation has great virtue. Microwave irradiation synthesis does not only require the least time, but also has the greatest yield. A Schiff base was synthesized from p-Chlorobenzaldehyde and o-Phenylenediamine. Metal complexes of the Schiff base were prepared from chloride salts of Ni (II) in ethanol. The chemical structures of the Schiff base ligand and its metal complexes were confirmed by spectroscopic analysis. The compounds were evaluated for their antimicrobial study.

Keywords: Schiff base, p-Chlorobenzaldehyde, o-Phenylenediamnine, Microwave irradiation, Reflux, Stirring, Grinding.