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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS: SEPTEMBER ISSUE PUBLISHED

SEPTEMBER 2024 Issue has been successfully launched on 1 SEPTEMBER 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

VALIDATION OF UV SPECTROSCOPIC METHOD OF ANALYSIS FOR ASSAY AND DISSOLUTION OF ACECLOFENAC TABLET

*Kaushik Rasiklal Valambhia

P.O.Box 38203, Dar-es-Salaam United Republic of Tanzania.

ABSTRACT

Aceclofenac is a non steroidal anti-inflammatory drug with good analgesic and anti-rheumatic properties. Various methods for analysis of the same are available but are time consuming and expensive due to solvents used .Here I have developed a new, precise and simple UV spectrophotometric method for estimation of aceclofenac from tablet formulation. The drug obeyed the Beerâ€™s law and showed good correlation. It showed absorption maxima at 276 nm; in methanol for assay and Phosphate buffer pH 6.8 for dissolution. The linearity was observed between 0-120 mcg/ml. The results of analysis were validated by recovery studies. The recovery was more than 99%. The method was found to be very simple. Accurate, precise, economical and robust.

Keywords: Aceclofenac, UV-Vis spectrophotometry Recovery.

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