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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

VALIDATION OF UV SPECTROSCOPIC METHOD OF ANALYSIS FOR ASSAY AND DISSOLUTION OF ACECLOFENAC TABLET

*Kaushik Rasiklal Valambhia

P.O.Box 38203, Dar-es-Salaam United Republic of Tanzania.

ABSTRACT

Aceclofenac is a non steroidal anti-inflammatory drug with good analgesic and anti-rheumatic properties. Various methods for analysis of the same are available but are time consuming and expensive due to solvents used .Here I have developed a new, precise and simple UV spectrophotometric method for estimation of aceclofenac from tablet formulation. The drug obeyed the Beerâ€™s law and showed good correlation. It showed absorption maxima at 276 nm; in methanol for assay and Phosphate buffer pH 6.8 for dissolution. The linearity was observed between 0-120 mcg/ml. The results of analysis were validated by recovery studies. The recovery was more than 99%. The method was found to be very simple. Accurate, precise, economical and robust.

Keywords: Aceclofenac, UV-Vis spectrophotometry Recovery.

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