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BISMUTH (III) BROMIDE-CATALYZED AN EFFICIENT PROTOCOL FOR THE SYNTHESIS OF HIGHLY FUNCTIONALIZED PIPERIDINES
Venkata Reddy H, Rajendraprasad K.J, Shekar H.S, and Manjula Krishnappa*
ABSTRACT The new protocol has been developed for the synthesis of highly functionalized piperidines using Bismuth (III) bromide as a catalyst, using three component combination of ß-ketoester with various aryl aldehydes and substituted aryl amines in ethanol at 80oC. The reaction proceeded in short period of time with high yields using low toxicity bismuth compound. Keywords: Bismuth (III) bromide (BiBr3), Functionalized piperidines, ß-ketoester, aryl aldehydes and aryl amines. [Download Article] [Download Certifiate] |