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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

ANTIMUTAGENIC ACTIVITY OF ETHANOLIC EXTRACT OF CARALLUMA FIMBRIATA

S. Sasikala*, Dr. S. Gowri and M. Thiruselvi

ABSTRACT

In the present investigation the potential activity of ethanolic extract of Caralluma fimbriata for its antimutagenicity using Salmonella typhimurium was determined. This is mainly based on the reversion of mutant cells by mutagenic agents. It was found that the extract inhibit the revertant formation produced by direct acting mutagens such as sodium azide, Ethidium bromide and Hydroxyl amine. The extracts showed more than 95% inhibition of mutagenicity at a concentration of 1mg/plate and the activity decreased with decreased concentration. It could also produce significant inhibition of mutagenicity and the results are highly significant.

Keywords: Caralluma fimbriata, Salmonella typhimurium, antimutagenicity, Sodium azide, Ethidium bromide and Hydroxyl amine.

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