Abstract

A STUDY ON ETIOLOGY OF URINARY TRACT INFECTIONS

Pyde Acharya Nagarjun*

ABSTRACT

Urinary tract infection is the most common cause of infection in nursing home residents and the most common source of bacteremia in the elderly population. Escherichia coli (E.coli) is the most common cause of uncomplicated UTI, whereas antibiotic-resistant Enterobacteriaceae, Enterococci and Candida species often are the causes of complicated UTI. This study was to determine and analyze the distribution and antibiotic susceptibility patterns of bacterial strains isolated from patients with community acquired urinary tract infection (UTIs) at the Institute Of Preventive Medicines, Hyderabad. Many urological abnormalities may be associated with complicated urinary infection. There is a wide spectrum of potential infecting organisms and isolated bacteria tend to be more resistant to antimicrobial therapy. Morbidity and infection outcomes in subjects with complicated urinary infection are principally determined by the underlying abnormality rather than the infection. Principles of management include uniform collection of a urine specimen for culture before antimicrobial therapy, characterization of the underlying genitourinary abnormality and nontreatment of asymptomatic bacteriuria except before an invasive genitourinary procedure. The antimicrobial regimen is determined by clinical presentation, patient tolerance, renal function and known or anticipated infecting organisms. If the underlying abnormality contributing to the urinary infection cannot be corrected, then early post-treatment recurrence of infection is anticipated. The treatment of complicated urinary infection is individualized depending on patient variables and the infecting organism. Further clinical investigations are necessary to assist in determining optimal antimicrobial regimens.

Keywords: Antimicrobials, Complicated, E.coli, Urinary tract infection.